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DOI: 10.4244/EIJV9I2A47

Percutaneous treatment of paravalvular leaks after transcatheter aortic valve implantation with the CoreValve self-expanding bioprosthesis

Francesco Saia*, MD, PhD; Cinzia Marrozzini, MD; Carolina Moretti, MD; Barbara Bordoni, MD; Cristina Ciuca, MD; Antonio Marzocchi, MD

Mild-to-moderate aortic regurgitation (AR) after transcatheter aortic valve implantation (TAVI) is common and often clinically silent. Higher-degree AR may occur, with significant haemodynamic and clinical consequences. Treatment of this condition is challenging and there are no evidence-based therapeutic options. This image illustrates the successful percutaneous management of clinically relevant paravalvular leaks (PVL) after implantation of the CoreValve bioprosthesis (Medtronic, Minneapolis, MN, USA) with the use of vascular plug devices.

Conflict of interest statement

The authors report no financial relationships or conflicts of interest regarding the content herein.

Figure 1. Examples of successful percutaneous closure of severe paravalvular leak (PVL) after transcatheter aortic valve implantation (TAVI) using two different Amplatzer™ vascular plug (AVP) devices (St. Jude Medical, St. Paul, MN, USA). A) The Amplatzer™ Vascular Plug 4. B) The frame of the bioprosthesis was crossed using an Amplatz Left diagnostic catheter, with the help of a hydrophilic wire. C) Catheter exchange into the left ventricle was performed with a 260 cm hydrophilic wire, and a 6 mm device was advanced through a 6 Fr multipurpose PCI catheter. The distal part of the AVP4 device is visible (arrow). D) Position of the device across the valve frame after its release. E) Closure of a PVL with an AVP2 device (box). The device was released with the proximal disc within the aortic side of the frame and the other two lobes sitting below the severely calcified native valve annulus. F and G) Drawings superimposed on the angiography to highlight the mechanism and the site of aortic regurgitation (F) and the position of the vascular plug (G). The lines show the presence of an angle between the aortic annulus plane (dotted line) and the bioprosthetic valve plane (solid line).

Volume 9 Number 2
Jun 28, 2013
Volume 9 Number 2
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Hello , I'm Cory and I will do my best to answer your questions about this article. Please remember that this is an experimental feature, and that I'm still learning.
What are the key steps involved in the percutaneous closure procedure?
What are the potential advantages of using vascular plug devices for this purpose?
How do the authors describe the mechanism and site of aortic regurgitation in relation to the bioprosthetic valve?
Are there any other percutaneous or surgical options for managing paravalvular leaks after TAVI?
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